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US 2010/0136120 A1Published application
Compositions and methods for forming and strengthening bone
AssigneeMarfly 2, LP
InventorJ. Alexander Marchosky
Life of this patent
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Abstract
Compositions are provided which stimulate bone growth. Also provided are methods for utilizing the compositions for filling in bone defects, promoting rapid fusion of bone fractures, grafts, and bone-prostheses, and promoting strengthening of osteoporotic bones.
Claims25
A composition comprising:
- (a) one or more materials selected from the group consisting of fibroblast growth factors, vascular endothelial growth factors, endothelial cell growth factors, transforming growth factors, chitosan, bone, platelet derived endothelial-growth factors, placental growth factors, angiogenin, interleukin-8, granulocyte colony-stimulating growth factor, and supernatant fluid from a culture of cells known to produce angiogenic factors;
- and
- (b) a material comprising demineralized bone matrix, non-decalcified bone matrix, cancellous bone, and hyaluronic acid or a salt thereof.
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Dependencies are inferred from the claim text.