Formulation for retinoid-containing soft gelatin capsules
AssigneeGlaxo Group Limited
InventorsGünter Ditzinger, Bernhard Gabriel, Anne-Hortense Schmitt-Hoffmann, Lutz Wevelsiep
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Abstract
A new pharmaceutical formulation for retinoid-containing soft gelatin capsules is disclosed. The new formulation comprises a soft gelatin capsule filled with a fill mass comprising a retinoid as an active ingredient, a natural vegetable oil, a partially hydrogenated natural vegetable oil and medium chain triglycerides. Optionally, the new formulation also comprises a natural wax. In a particularly preferred embodiment, the soft gelatin capsule comprises pig gelatin in the capsule shell in combination with the above fill mass.
Claims18
Pharmaceutical formulation for retinoids comprising a soft gelatin capsule filled with a fill mass comprising a retinoid as an active ingredient, a natural vegetable oil, a partially hydrogenated natural vegetable oil and medium chain triglycerides.
Pharmaceutical formulation according to any one of claims to 15, wherein the fill mass comprises about 1 to 10 percent by weight, in particular about 3 to 6 percent by weight, especially preferred about 4 percent by weight, of the natural wax.
Dependencies are inferred from the claim text.