Liquid Therapeutic Composition
AssigneeNovartis AG
InventorsSatisha Puttachari, Shripad Naik, Christopher Pulford
Life of this patent
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Abstract
A liquid composition includes a therapeutic component dispersed in a liquid carrier system. The liquid carrier system is made up of water and a solvent. The solvent includes at least 90 wt % propylene glycol and less than 2 wt % ethanol, if ethanol is present in the solvent. The therapeutic component has acetaminophen and phenylephrine. The weight ratio of solvent to phenylephrine is between 100:1 to 2000:1. The weight ratio of solvent to acetaminophen is between 5:1 and 25:1.
Claims17
A liquid composition comprising a therapeutic component dispersed in a liquid carrier system, wherein:
- the liquid carrier system comprising water and a solvent,
- the solvent comprising at least 90 wt % propylene glycol and less than 2 wt % ethanol, if ethanol is present in the solvent, and
- the therapeutic component comprising acetaminophen and phenylephrine,
- the weight ratio of solvent to phenylephrine is between 100:1 to 2000:1, and
- the weight ratio of solvent to acetaminophen is between 5:1 and 25:1.
A method of treating a cold or cold-like symptoms in an individual, the method comprising administering to the individual a safe and effective amount of a liquid composition comprising a therapeutic component dispersed in a liquid carrier system, wherein:
- the liquid carrier system comprising water and a solvent,
- the solvent comprising at least 90 wt % propylene glycol and less than 2 wt % ethanol, if ethanol is present in the solvent, and
- the therapeutic component comprising acetaminophen and phenylephrine,
- the weight ratio of solvent to phenylephrine is between 100:1 to 2000:1, and
- the weight ratio of solvent to acetaminophen is between 5:1 and 25:1.
A soft gelatin capsule comprising a soft gelatin shell and between 5 ml and 30 ml a liquid composition comprising a therapeutic component dispersed in a liquid carrier system, wherein:
- the liquid carrier system comprising water and a solvent,
- the solvent comprising at least 90 wt % propylene glycol and less than 2 wt % ethanol, if ethanol is present in the solvent, and
- the therapeutic component comprising acetaminophen and phenylephrine,
- the weight ratio of solvent to phenylephrine is between 100:1 to 2000:1, and
- the weight ratio of solvent to acetaminophen is between 5:1 and 25:1,
- wherein the liquid composition is enclosed by the soft gelatin shell.
Dependencies are inferred from the claim text.