Liposome for induction of cell-mediated immunity
OwnerHideyoshi Harashima, Kentaro Kogure +4inventors
InventorsHideyoshi Harashima, Kentaro Kogure, Takashi Nakamura, Rumiko Moriguchi, Kohei Ono, Homhuan Atthachai
Life of this patent
Estimating the term…
Abstract
Disclosed is a liposome which includes an antigenic substance therein and has, on its surface, a peptide containing several contiguous arginine residues. The liposome enables an antigen-presenting cell to achieve the selective antigen presentation through an MHC Class-I molecule, and can induce a cell-mediated immunity specifically. The liposome can also induce the antigen presentation by a matured dendritic cell.
Claims9
A liposome having a peptide on a surface thereof, comprising several contiguous arginine residues having an encapsulated antigenic substance.
Dependencies are inferred from the claim text.