Virulence of streptococci
AssigneeID-Lelystad, Instituut voor Dierhouderij en Diergezondheid B.V.
InventorHilda Elizabeth Smith
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Abstract
The invention relates to the field of diagnosis of and vaccination against Streptococcal infections and to the detection of virulence markers of Streptococci. The invention discloses a method for modulating virulence of a Streptococcus, the method comprising modifying a genomic fragment of Streptococcus wherein the genomic fragment comprises at least a functional part of a fragment identifiable by hybridization in Streptococcus suis to a nucleic acid or fragment thereof as shown in FIG. 5.
Claims20
A method for modulating virulence of a Streptococcus comprising:
- modifying a means that imparts virulence to the Streptococcus.
A method for modulating virulence of a Streptococcus comprising:
- modifying a genomic fragment of the Streptococcus;
- wherein the genomic fragment comprises a nucleic acid having a sequence, the sequence selected from the group of sequences consisting of SEQ ID NO:
- 11, SEQ ID NO:
- 12 and functional fragments thereof.
A method for assaying virulence of a Streptococcus comprising:
- assaying a means that imparts virulence to the Streptococcus.
A method for assaying virulence of a Streptococcus comprising:
- assaying a genomic fragment of the Streptococcus;
- wherein the genomic fragment comprises a nucleic acid having a sequence, the sequence selected from the group of sequences consisting of SEQ ID NO:
- 11, SEQ ID NO:
- 12 and functional fragments thereof.
An isolated or recombinant nucleic acid having a sequence selected from the group of sequences consisting of SEQ ID NO:
- 11, SEQ ID NO:
- 12 and functional fragments thereof.
Dependencies are inferred from the claim text.