Selective Inhibition of Histone Deacetylase 6 for Ocular Neuroprotection or for Treatment or Control of Glaucoma
OwnerStephen P. Bartelsinventor
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Abstract
A composition comprises a material capable of selectively controlling a level or activity of HDAC6 in an ocular environment for effecting ocular neuroprotection in subjects in risk of developing or worsening an ocular neurodegenerative condition, or for treating or controlling glaucoma. Such a composition can be administered to a patient in combination with another therapy directed at providing ocular neuroprotection or treating or controlling glaucoma.
Claims28
A composition comprising a material capable of selectively controlling a level of HDAC6 or of HDAC6 activity in an ocular environment when applied thereto, wherein the material is present in an effective amount for effecting ocular neuroprotection.
A method for effecting ocular neuroprotection, or for treating or controlling glaucoma, in a subject in need thereof, the method comprising administering to an ocular environment of said subject a composition that comprises a selective inhibitor of HDAC6 in an effective amount and at an effective frequency to effect said neuroprotection or to treat or control said glaucoma.
Dependencies are inferred from the claim text.