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US 2010/0136000 A1Published application
Treatment of follicular lymphomas using inhibitors of the lt pathway
AssigneesNew York University, Biogen Idec MA Inc.
InventorsJeffrey BROWNING, Jeanette THORBECKE, Vincent TSIAGBE
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Abstract
Therapeutic uses of inhibitors of the lymphotoxin pathway to treat tumors, specifically to treat follicular lymphomas.
Claims29
A method for arresting or reducing the advancement, severity or effects of a tumor comprising the administration to a subject of an effective amount of a composition which inhibits the interaction between LT-β and its receptor.
(canceled)
(canceled)
A method for altering the architecture of the organs of the immune system by administering (a) an inhibitor of the interaction between LT-β and its receptor;
- and (b) an inhibitor of the signaling pathway of an additional member of the TNF family of ligands and receptors.
Dependencies are inferred from the claim text.