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US 2010/0135908 A1Published application
Delivery devices for modulating inflammation
AssigneeSearete LLC, a limited liability corporation of the State of Delaware
InventorsRoderick A. Hyde, Stephen L. Malaska, Elizabeth A. Sweeney, Lowell L. Wood, JR.
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Abstract
Certain embodiments disclosed relate to compositions, including therapeutic compositions, methods, devices, and systems that modulate at least one inflammatory response or reaction. According to various embodiments, the compositions, methods, devices, and systems relate to modulating one or more of Toll-like receptors, Src family kinases, NF-kB molecules, proteases, or proteasomes.
Claims35
A drug delivery device, comprising:
- at least one reservoir configured to receive, retain and dispense at least one therapeutic composition, including one or more outlets operably associated with the at least one reservoir;
- wherein the at least one reservoir includes at least one therapeutic composition including at least one first agent configured to modulate the activity of one or more Toll-like receptors;
- at least one second agent configured to modulate the activity of one or more Src family kinases;
- and
- at least one third agent configured to modulate the activity of one or more NF-kB molecules.
2 more elements
Dependencies are inferred from the claim text.