Mass spectrometry apparatus
AssigneeShimadzu Corporation
InventorMayumi MATSUI
Life of this patent
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Abstract
A mass spectrometry apparatus configured to allow a user to designate an upper limit value UL together with a lower limit value, as a peak sorting condition. A data processing section is operable to determine whether respective peak intensities of a plurality of peaks appearing on a mass spectrum fall within an intensity range Ath defined by upper and lower limit values UL, LL, and exclude any peak out of the intensity range Ath. The remaining ions are selected as precursor ions, for example, in descending or ascending order of peak intensity so as to perform an MS2 analysis. The upper limit UL is adequately set to allow the MS2 analysis for a sample component with a low concentration, by priority, while avoiding a sample component exhibiting a high intensity and having no need for the MS2 analysis.
Claims4
A mass spectrometry apparatus designed to determine one or more precursor ions based on an MSn−1 spectral data acquired through an MSn−1 analysis, and inducing fragmentation of the precursor ions to perform an MSn analysis (wherein n is an integer of 2 or more), comprising:
- a) setting means operable to allow a user to input and set an upper limit and a lower limit value of a signal intensity on an MSn−1 spectrum, or to directly input and set an intensity range having upper and lower thresholds of a signal intensity on an MSn−1 spectrum;
- b) peak sorting means operable to sort a peak having a peak intensity which falls within an intensity range defined by the upper and lower limit values or the directly input/set intensity range, from a plurality of peaks appearing in an acquired MSn−1 spectrum;
- and
- c) analysis control means operable to controllably allow an ion having a mass corresponding to the peak sorted by the peak sorting means to be selected as a precursor ion so as to perform the MSn analysis.
A mass spectrometry apparatus designed to determine one or more precursor ions based on an MSn−1 spectral data acquired through an MSn−1 analysis, and inducing fragmentation of the precursor ions to perform an MSn analysis (wherein n is an integer of 2 or more), comprising:
- a) setting means operable to allow a user to input and set at least a lower limit value of a signal intensity on an MSn−1 spectrum;
- b) peak sorting means operable to sort one or more peaks each having a peak intensity equal to or greater than the lower limit value, from a plurality of peaks appearing in an acquired MSn−1 spectrum;
- and
- c) analysis control means operable to controllably allow ions having respective masses corresponding to the peaks sorted by the peak sorting means to be selected as precursor ions in ascending order of peak intensity so as to perform the MSn analysis.
Dependencies are inferred from the claim text.