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US 2010/0133427 A1Published application
Extended dynamic range light detection systems and methods
AssigneeBio-Rad Laboratories, Inc.
InventorsPaul Patt, Joel Talacki
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AssigneeBio-Rad Laboratories, Inc.
InventorsPaul Patt, Joel Talacki
Estimating the term…
Systems and methods for detecting and measuring light emitted from a sample and having a large dynamic range, e.g., a range of luminous intensity covering six or more orders of magnitude, that may be difficult to fully detect using a single detector with a limited detection range. Simultaneous measurements of the emitted light in two intensity ranges are performed using two detectors, e.g., one including a photomultiplier tube (PMT) and the other including a solid state detector such as a photodiode. A beam splitting element directs light emitted from a sample under investigation to both detectors simultaneously such that a portion of the light impinges on the first detector and a second portion of the light impinges on the second detector. A processor receives output signals from the two detectors and provides an output representing the luminous intensity of the sample over a detection range greater than the detection range of each individual detector, thereby providing a detection system having an enhanced dynamic range.
A light detection system with large dynamic range detection capability, comprising:
A method of detecting light emitted from a sample using a detection system proximal to the sample, wherein the detection system includes a first detection element capable of detecting light over a first intensity range and a second detection element capable of detecting light over a higher intensity range than the first detection element, wherein the second light detection element includes a solid-state detection element, the method comprising:
Dependencies are inferred from the claim text.