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US 2010/0133161 A1Published application
Metal-Coated Superficially Porous Supports as a Medium for HPLC of Phosphorus-Containing Materials
AssigneeAgilent Technologies, Inc.
InventorsBarry E. Boyes, James D. Martosella, Susanne C. Moyer
Life of this patent
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Abstract
Methods for the separation of biological materials from a sample mixture using a superficially porous particle coated (or clad) with a metal are provided herein. Methods using the support as a chromatographic column are also provided.
Claims11
1-13. (canceled)
A metal-coated superficially porous particle for separating biological material from a sample, comprising:
- a) an internal non-porous silica core;
- and
- b) an external porous silica layer comprising a metal-coating, wherein the metal of the metal coating is not bound to said porous silica layer by a chelating ligand.
Dependencies are inferred from the claim text.