Compositions and methods for treatement of cancer
AssigneesYissum Research Development Company of the Hebrew University of Jerusalem, Theravir Management L.P.
InventorsZichria Zakay-Rones, Amos Panet, Evgeniya Greenbaum, Eithan Galun, Arnold I. Freeman, Linda Rasooly, Charles S. Irving
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Abstract
The present invention discloses lentogenic viral strains useful in the treatment of cancer. A preferred viral strain of Newcastle disease Virus (NDV) is specifically characterized in terms of biological activities. The present invention further discloses treatment of cancer by application of a clonal NDV strain to tumors. According to an alternative preferred embodiment the use of at least one isolated viral protein or subunit or analog thereof, or an isolated polynucleotide encoding same, is used in the treatment of cancer.
Claims13
A composition for the treatment of cancer comprising at least one isolated viral glycoprotein or a subunit or analog thereof having oncolytic activity and a suitable carrier.
Dependencies are inferred from the claim text.