Back to results
US 2010/0076225 A1Published application
Polymorphs of atomoxetine hydrochloride
OwnerJudith Aronhime, Stefano Bianchi +4inventors
InventorsJudith Aronhime, Stefano Bianchi, Eugenio Castelli, Paola Daverio, Silvia Mantovani, Adrienne Kovacsne-Mezei
Life of this patent
Estimating the term…
Abstract
The present invention provides novel crystalline polymorph forms of atomoxetine hydrochloride denominated Forms B and C and methods for their preparation, as well as methods for the preparation of Form A. The present invention provides pharmaceutical compositions that comprise atomoxetine hydrochloride Form B, Form C, or mixtures thereof that can be used to treat attention deficit/hyperactivity disorder.
Claims5
1-8. (canceled)
Atomoxetine hydrochloride prepared according to a process comprising the steps of:
- a) combining atomoxetine hydrochloride with water at a temperature of about 40° C. to about 60° C. to obtain a mixture;
- b) cooling the mixture to about room temperature to obtain a precipitate;
- and
- c) recovering atomoxetine hydrochloride.
1 more element
Dependencies are inferred from the claim text.