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US 2010/0076092 A1Published application
Lipid-derived nanoparticles for brain-targeted drug delivery
OwnerJayanth Panyam, Mahesh D. Chavanpatilinventors
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Abstract
Disclosed herein are compositions and methods useful for the delivery of compounds across the blood brain barrier. Nanoparticles comprising lipids, such as brain lipids, are used to encapsulate drugs and to facilitate drug delivery to the brain.
Claims19
A nanoparticle composition comprising:
- a) a brain lipid,
- b) a supplemental lipid,
- c) a PEG-conjugated lipid, and
- d) a drug or therapeutic compound.
1 more element
A method of delivering drugs or therapeutic compounds to the brain of an individual comprising:
- a) providing a nanoparticle composition, and
- b) administering the nanoparticle composition to an individual, wherein at least a portion of the therapeutic composition is delivered to the brain.
Dependencies are inferred from the claim text.