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US 2010/0076079 A1Published application
Pharmaceutical Compositions Of Short-Acting Sedative Hypnotic Agent
AssigneeTheravance, Inc.
InventorsThomas E. Jenkins, Jennifer Bolton
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Abstract
The invention provides pharmaceutical compositions comprising a phenylacetic acid ester compound useful for inducing or maintaining general anesthesia or sedation in mammals, methods for preparing such compositions, and methods for inducing or maintaining anesthesia or sedation using such compositions.
Claims23
A pharmaceutical composition comprising:
- [4-[(N,N-diethylcarbamoyl)methoxy]-3-ethoxyphenyl]acetic acid propyl ester;
- a water-immiscible solvent;
- an emulsifier;
- a tonicity modifier;
- between about 0.05% and about 0.2% by weight histidine;
- and
- water,
- wherein the pH of the composition is greater than about 7;
- and wherein the composition optionally further comprises a preservative.
6 more elements
23-25. (canceled)
Dependencies are inferred from the claim text.