Forskolin dosing regimen in open angle glaucoma and patient compliance methods thereof
OwnerMuhammed Majeedinventor
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Abstract
Disclosed is an optimal dosing regimen for forskolin to ensure the most optimal pharmacokinetic/pharmacodynamic responses desired in the therapeutic management of open angle glaucoma. The optimal dosing regimen involves the ocular application of 2% forskolin solubilized using randomly-methylated beta-cyclodextrins one drop once a day to patients requiring therapy for open angle glaucoma. Also disclosed are methods of promoting patient compliance, in particular geriatric and pediatric patient compliance during the therapeutic management of glaucoma using an optimal dosing regimen for forskolin to ensure the best pharmacokinetic/pharmacodynamic effects, devoid of systemic side-effects encountered with the currently used beta-blockers or prostaglandins.
Claims5
Optimized forskolin dosage regimens for the most optimal pharmacodynamic/pharmacokinetic responses desired in the therapeutic management of open angle glaucoma glaucoma, said dosage regimen comprising 2% w/w forskolin solubilized using randomly-methylated beta-cyclodextrins for use as an ocular application one drop once a day requiring therapy for open angle glaucoma.
A method to promote patient compliance during the therapeutic management of open angle glaucoma, said method involving a specific pharmaceutical dosage regimen comprising 2% w/w forskolin solubilized using randomly-methylated beta-cyclodextrins for use as an ocular application one drop once a day in patients requiring therapy for open angle glaucoma.
Pharmaceutical dosage regimens of forskolin which are designed to increase patient compliance during forskolin therapy for glaucoma, said dosage regimens comprising 2% w/w forskolin solubilized using randomly-methylated beta-cyclodextrins for use as an ocular application one drop once a day in patients requiring therapy for open angle glaucoma.
A method to treat open angle glaucoma, said method comprising the ocular administration in patients in need of such treatment, an optimized forskolin dosage regimen comprising 2% w/w forskolin solubilized using randomly-methylated beta-cyclodextrins one drop once a day.
Dependencies are inferred from the claim text.