Amorphous 1-(9H-carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol phosphate salt
OwnerSankar Reddy Budidet, Yallappa Somappa Somannavar +2inventors
InventorsSankar Reddy Budidet, Yallappa Somappa Somannavar, Ramesh Dandala, Sivakumaran Meenakshisunderam
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Abstract
The present invention relates to a novel amorphous form of 1-(9H-carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol phosphate (Carvedilol dihydrogen phosphate) of Formula (I), and a process for the preparation thereof.
Claims17
1) Amorphous 1-(9H-carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol phosphate.
3) A process for the preparation of amorphous form of 1-(9H-carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol phosphate salt (Carvedilol dihydrogen phosphate) Formula (I),
- which comprises,
- i) reacting 1-(9H-carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol (II)
- with phosphoric acid of formula (III)
- ii) isolating amorphous Carvedilol dihydrogen phosphate.
Dependencies are inferred from the claim text.