Novel pyridine derivatives and pyrimidine derivatives (3)
AssigneeEisai R&D Management Co., Ltd.
InventorsTomohiro MATSUSHIMA, Keiko Takahashi, Setsuo Funasaka, Hiroshi Obaishi, Shuji Shirotori
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AssigneeEisai R&D Management Co., Ltd.
InventorsTomohiro MATSUSHIMA, Keiko Takahashi, Setsuo Funasaka, Hiroshi Obaishi, Shuji Shirotori
Estimating the term…
A compound represented by the following formula, or a salt thereof or a hydrate of the foregoing, has excellent hepatocyte growth factor receptor (HGFR) inhibitory activity, and exhibits anti-tumor activity, angiogenesis inhibitory activity, and cancer metastasis inhibitory activity. R1 represents a 3- to 10-membered non-aromatic heterocyclic group or the like; R2 and R3 represent hydrogen; R4, R5, R6, and R7 may be the same or different and each represents hydrogen, halogen, C1-6 alkyl or the like; R8 represents hydrogen or the like; R9 represents a 3- to 10-membered non-aromatic heterocyclic group or the like; n represents an integer of 1 or 2; X represents —CH═, nitrogen or the like.
A compound represented by the following formula or a salt thereof:
Dependencies are inferred from the claim text.