Use of Nutritional Compositions for Preventing Disorders
AssigneeN.V. Nutricia
InventorsRenate Maria Louise Zwijsen, Hubertus Josephus Maria Van De Heijning, Eline Marleen Van Der Beek, Katrien Maria Jozefa Van Laere, Günther Boehm
Life of this patent
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Abstract
The present invention relates to a method for preventing and/or treating visceral adiposity by administering a certain nutritional composition to an infant with the age between 0 and 36 months, and preventing the occurrence of diseases later in life.
Claims23
A method for preventing and/or treating visceral adiposity and/or preventing and/or treating accumulation of visceral fat mass to an excessive amount in a human infant from birth until age 36 months, comprising feeding the infant with a nutritional composition comprising a lipid, protein and digestible carbohydrate component, wherein:
- (a) the lipid component provides 35 to 55% of the total calories,
- (b) the protein component provides 5 to 15% of the total calories and
- (c) the digestible carbohydrate component provides 30 to 60% of the total calories, and
- wherein the lipid component comprises less than 14.5 wt. % linoleic acid based on total fatty acids, and a weight ratio of linoleic acid (LA) to alpha-linolenic acid (ALA) is between 2 and 6. and
- wherein said feeding
- (i) prevents and/or treats said visceral adiposity;
- (ii) prevents and/or treats the accumulation of said excessive visceral fat tissue;
- and/or
- (ii) decreases the ratio of said visceral fat area to subcutaneous fat area.
A method for preventing the development of a disorder in a human subject, comprising feeding to a non-obese subject aged below 36 months or subject aged above 36 month a nutritional composition comprising a lipid, a protein and a digestible carbohydrate component, wherein
- (a) the lipid component provides 35 to 55% of the total calories,
- (b) the protein component provides 5 to 15% of the total calories and
- (c) the digestible carbohydrate component provides 30 to 60% of the total calories,
- wherein the lipid component comprises
- (i) a LA to ALA weight ratio of 2 to 6;
- (ii) less than 14.5 wt. % LA based on total fatty acids;
- (iii) long chain polyunsaturated fatty acids (LC-PUFA);
- and, optionally
- (iv) 10-50 wt. % medium chain fatty acids (MCFA),
- wherein said disorder is selected from the group consisting of type 2 diabetes, fasting hyperglycemia, insulin resistance, visceral adiposity, hyperinsulinemia, hypertension, cardiovascular disease, cerebrovascular disease, arthrosclerosis, dyslipidemia, hyperuricemia, fatty liver, osteoarthritis and sleep apnea.
A method for preventing development of a disorder in a human aged above 36 months, comprising, feeding to a non-obese human aged below 36 months a composition comprising galactooligosaccharide and/or long chain polyunsaturated fatty acid,
- wherein said disorder is selected from the group consisting of type 2 diabetes, fasting hyperglycemia, insulin resistance, visceral adiposity, hyperinsulinemia, hypertension, cardiovascular disease, cerebrovascular disease, arthrosclerosis, dyslipidemia, hyperuricemia, fatty liver, osteoarthritis and sleep apnea.
Dependencies are inferred from the claim text.