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AssigneeNational University of Singapore
InventorsDieter Trau, Wen-Tso Liu, Kian Kok Johnson Ng
Estimating the term…
A process for making a micro-array. The process comprises the step of depositing a population of microbeads on a substrate having at least one fiducial. The population being comprised of at least two sub-populations, preferably multiple sub-populations, each comprising a known active agent capable of specific binding with at least one target analyte. The said subpopulations are deposited sequentially and at discrete periods of each other. The process also comprises the step of making images of the substrate after deposition of each subpopulation. The images are then compared using the fiducial as a reference to thereby determine the location of each microbead and to identify the subpopulation, and its known active agent, based on differences between each image. Also disclosed in a system for using the microarray.
A process for making a micro-array comprising the steps of:
A microarray for use in a system for identifying the presence of one or more target analytes in a sample, the microarray comprising a random population of microbeads disposed on a substrate surface having at least one fiducial, said population being comprised of at least two sub-populations each comprising a known active agent capable of specific binding with at least one target analyte, wherein each of said subpopulations have been deposited sequentially and at discrete periods of each other to enable the location of each microbead and its respective sub-population to be determined relative to said fiducial from comparative images taken during each discrete deposition period.
A microarray system for identifying the presence of one or more target analytes in a sample comprising:
21-22. (canceled)
Dependencies are inferred from the claim text.