Device and method for growing and analyzing cells
AssigneesThe Trustees of Columbia University in the City of New York, The Research Foundation of State University of New York
InventorsRichard B. Robinson, Lev Protas, Michael R. Rosen, Ira S. Cohen, Peter R. Brink
Life of this patent
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Abstract
A device and method for analyzing cells includes a housing with a chamber, a barrier supported by a frame disposed within the chamber, and a plate arranged at a bottom surface of the housing interior of the chamber. The plate is adapted to receive and sustain cells and the barrier separates the plate into at least two contiguous separate areas. In some embodiments, a thin rubber strip is arranged at the bottom edge of the barrier, which facilitates control of the area in which each cell type is grown, the size of the gap between the cells, and helps prevents over growth of the two cell types on to each other.
Claims15
A method, comprising:
- a) placing a barrier on a plate so as to divide the plate into at least two separate areas;
- b) forming cells on the plate on opposite sides of the barrier;
- c) removing the barrier after forming the cells;
- and
- d) detecting at least one parameter of the cells after removing the barrier.
A device, comprising:
- a housing including a chamber;
- a removable barrier disposed within the chamber;
- a plate arranged at a bottom surface of the housing interior of the chamber;
- wherein the plate is adapted to receive and sustain cells and the barrier separates the plate into at least two contiguous separate areas.
A device for use with a plate adapted to receive and sustain cells, comprising:
- a housing including a chamber;
- and
- a removable barrier disposed within the chamber and adapted to seal against the plate and separate the plate into at least two contiguous separate areas.
Dependencies are inferred from the claim text.