Cell And Enzyme Compositions For Modulating Bile Acids, Cholesterol and Triglycerides
AssigneeUAS Laboratories LLC
InventorsSatya Prakash, Mitchell Lawrence Jones
Life of this patent
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Abstract
The invention relates to immobilized or encapsulated enzyme and/or cells to lower bile acids and cholesterol. The invention also relates to methods of quantitatively measuring bile acids. The invention provides a composition for decreasing the amount of a target compound in the gastrointestinal tract of an animal, comprising: a) a biologically active agent which decreases the amount of the target compound; b) a retainer for retaining the biologically active agent by contacting the agent to limit movement of the agent; and c) a carrier.
Claims50
1-25. (canceled)
A method for lowering of intraluminal bile acid of an animal comprising administering to the animal a bile acid lowering amount of a composition comprising
- (a) a bile-permeable microcapsule comprising (i) a bile acid degrading enzyme or (ii) a cell expressing a bile acid degrading enzyme;
- and
- (b) a carrier.
A method for lowering of intraluminal bile acid of an animal comprising administering to the animal a microcapsule comprising:
- (a) a bile acid lowering amount of a first bacteria that degrades bile salts and
- (b) a second bacteria that precipitates and binds the degraded bile salts.
(canceled)
(canceled)
34-78. (canceled)
Dependencies are inferred from the claim text.