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US 2010/0074848 A1Published application
X-ray contrast agent using gold nanoparticles and process for preparing the same
OwnerKwon-ha Yooninventor
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OwnerKwon-ha Yooninventor
Estimating the term…
Provided are an X-ray contrast agent using gold nanoparticles and a process for preparing the X-ray contrast agent. The X-ray contrast agent is prepared by capping gold nanoparticles with polyethylene glycol (PEG). The X-ray contrast agent is nontoxic and remains in a blood vessel for a long time so that the X-ray contrast agent can be usefully used as a computed tomography (CT) contrast agent for imaging blood vessels. Therefore, the X-ray contrast agent is useful for inspecting blood vessel structures and new blood vessels in a tumor, and obtaining perfusion images. In addition, gold provides better visibility than iodine when used in an X-ray contrast agent. Therefore, better x-ray images can be obtained using the X-ray contrast agent containing gold nanoparticles.
A contrast agent comprising a compound of methoxy polyethylene glycol sulfhydryl (MeO-PEG-SH)-gold nanoparticle colloid, wherein the compound is prepared by reacting MeO-PEG-SH with a gold nanoparticle colloid, and the MeO-PEG-SH and the compound are respectively represented by Formulas 1 and 2 below:
A process for preparing a contrast agent, comprising:
Dependencies are inferred from the claim text.