System for electrophoretic stretching of biomolecules using micro scale t-junctions
AssigneeMassachusetts Institute of Technology
InventorsPatrick Doyle, Jing Tang
Life of this patent
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Abstract
System for trapping and stretching biomolecules. A microfluidic device includes a symmetric channel forming a T-shaped junction at a narrow center region and three wider portions outside the center region. At least one power supply is provided to generate an electric potential across the T-shaped junction to create a local planar extensional field having a stagnation point in the junction whereby a biomolecule introduced into the microfluidic device is trapped at the stagnation point and stretched by the extensional field.
Claims14
System for trapping and stretching biomolecules comprising:
- a microfluidic device including a symmetric channel forming a T-shaped junction at a narrow center region and three wider portions outside the center region;
- and
- at least one power supply for generating an electric potential across the T-shaped junction to create a local planar extensional field having a stagnation point in the junction, whereby a biomolecule introduced into the microfluidic device is trapped at the stagnation point and stretched by the extensional field.
System for trapping and stretching biomolecules comprising:
- a microfluidic device including a full cross-slot channel including a junction;
- and
- at least one power supply for generating an electric potential across the junction to create a local planar extensional field having a stagnation point in the junction, whereby a biomolecule introduced into the microfluidic device is trapped at the stagnation point and stretched by the extensional field.
Dependencies are inferred from the claim text.