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US 2010/0063570 A1Published application
Coating on a balloon comprising a polymer and a drug
AssigneeAbbott Cardiovascular Systems Inc.
InventorsSTEPHEN D. PACETTI, John Stankus
Life of this patent
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Abstract
A coating on a balloon of a medical device is provided. The coating comprises a drug and a polymer. Also provided are methods of forming and using the coating.
Claims24
An medical device, comprising a balloon that comprises a coating on at least a portion of the surface of the balloon,
- wherein the coating comprises a bioactive agent and a biodurable polymer having a glass transition temperature (Tg) below 37° C. when hydrated,
- wherein the polymer comprises units from an alkoxy acrylate, a methacrylate, vinyl pyrrolidone, or polyethylene glycol acrylate (PEG-acrylate), and
- wherein the coating provides a burst release of the bioactive agent such that upon exposure to a physiological condition a majority of the bioactive agent is released from the coating within a period of about 60 seconds.
A method for fabricating a medical device comprising a balloon, comprising forming a coating on at least a portion of the surface of the balloon,
- wherein the coating comprises a bioactive agent and a biodurable polymer having a glass transition temperature (Tg) below 37° C. when hydrated,
- wherein the polymer comprises units from an alkoxy acrylate, a methacrylate, vinyl pyrrolidone, or polyethylene glycol acrylate (PEG-acrylate), and
- wherein the coating provides a burst release of the bioactive agent such that upon exposure to a physiological condition a majority of the bioactive agent is released from the coating within a period of about 60 seconds.
Dependencies are inferred from the claim text.