US 2010/0063370 A1 · Noise tolerant measurement

Abstract

The invention relates to statistical methods for fitting a mathematical model of the interaction of signals, such as optical signals, with tissue to detected signals or data related to the interaction. In particular it relates to statistical methods for fitting a mathematical model of the interaction of optical signals with tissue to actual signals, such as interferometric signals related to data optical scattering in tissue and their relationship to glucose concentration. It also relates to statistical methods for fitting a mathematical model of the interaction of optical signals with tissue to data such as the spectral distribution values of optical signals absorbed or scattered by tissue and their relationship to glucose concentration. The invention provides a practical non-invasive glucose measurement method and system. The invention also provides a measurement method and system that performs well in low signal-to-noise environments.

Claims16

Dependent claims

A method for processing signals detected by a non-invasive analysis system to determine the value of at least one attribute of a target in a low signal to noise environment, said method comprising:

generating a system model that represents the interaction of radiation scattered by said target and at least one reference signal associated with said non-invasive analysis system;
generating a noise model, said model comprised of noise associated with the non-invasive analysis system (system noise), noise associated with the target (target noise) and noise associated with the said scattered radiation (radiation noise);
generating a formula with a number of parameters, at least one of which is related to the value of said attribute of said target, said value to be determined;
using estimation techniques to fit said formula to signals detected by said non-invasive analysis system to determine the value of said attribute of said target;
and
outputting the value of said attribute of said target.

3 more elements

Dependencies are inferred from the claim text.

Noise tolerant measurement

Life of this patent

Noise tolerant measurement

Life of this patent

Abstract

Claims16