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US 2010/0063298 A1Published application
11c-labeled benzophenone/benzoxazole analogues as an inflammation imaging agent
AssigneeGe Healthcare Limited
InventorsFarhad Karimi, Bengt Langstrom
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Abstract
A method of preparing novel [11C]-labeled benzophenone/bezoxazole analogues is provided. The present invention also provides novel [11C]-labeled benzophenone/bezoxazole analogues prepared from the GMP synthesis method. Kit claims for preparing novel [11C]-labeled benzophenone/bezoxazole analogues and a method of use thereof are also provided.
Claims24
A compound of formula (I),
- wherein, * denotes a [11C], R1 & R2=alkyl, aryl, alkoxide, or a halide;
- R3═H, CH2COOH, CH2CONHR′, or CH2CONR′R″ wherein R′ or R″ is alkyl, aryl, or a combination thereof.
A compound of formula (II),
- wherein * denotes a [11C], R1 & R2=Alkyl, aryl, alkoxide, halide, or a combination thereof, and wherein n=1, 2, or 3.
8-9. (canceled)
15-16. (canceled)
-24. (canceled)
27-42. (canceled)
Dependencies are inferred from the claim text.