Carbazole-Derived Pharmaceutical Compositions

A method for the treatment, prevention and/or amelioration of a disease/disorder caused by a biochemical/biophysical pathological process occurring on, in or within lipid rafts comprising administering an amount of a pharmaceutical composition of a compound of one of the following formulae 2a, 2b, 2c and 2d:

• wherein
• R21a, R21b, R21c and R21d are a C5-30 hydrocarbon group, wherein one or more hydrogens are optionally replaced by halogen;
• X21d is O or a direct bond;
• R23a is H or C1-4 alkyl, wherein one or more hydrogens are optionally replaced by halogen or hydroxy or wherein two geminal hydrogens are optionally replaced by oxo;
• and
• each R2a, each R2b, each R2c and each R2d is independently H, C1-4 alkyl or O(C1-4 alkyl);
• or a pharmaceutically acceptable salt, solvate or prodrug thereof that is effective to treat, prevent and/or ameliorate such a disease/disorder.