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US 2010/0063125 A1Published application
Melatonin derivatives and their use as antioxidants
AssigneeUniversity of Sunderland
InventorsRosaleen Joy Anderson, Paul William Groundwater, David Antony Philip Small, Yu Gong
Life of this patent
Estimating the term…
Abstract
The present subject matter relates generally to antioxidant compounds having the formula (I): wherein each of R1, R2, R3, and R4 are as defined below. These compounds are potentially useful as, for example, antioxidants.
Claims43
A compound having the formula:
- wherein:
- R1 is hydrogen, alkyl, alkenyl, alkoxy, or alkenoxy;
- R2 is hydrogen, C1-C6 alkyl (CH2NO2)n, C2-C6 alkenyl (CH2NO2)n, C1-C6 alkyl-NHCOCH3, C2-C6 alkenyl-NHCOCH3, cycloalkyl, cycloalkenyl, aryl, heteroaryl, C1-C6 alkyl-NH2, or C2-C6 alkenyl- NH2;
- R3 is hydrogen, CO(C1-C6 alkyl), CO(C2-C6 alkenyl), C1-C6 alkyl-NHCOCH3, C2-C6 alkenyl-NHCOCH3, alkoxy, alkenoxy, C1-C6 alkyl (CH2NO2)n, C2-C6 alkenyl (CH2NO2)n, cycloalkyl, cycloalkenyl, aryl, or heteroaryl;
- R4 is alkoxy or alkenoxy;
- and
- N represents 1, 2, or 3;
- provided that:
- when R2 is CH2CH2NHCOCH3 then R1 and R3 are not both hydrogen;
- when R2 is CH2CH2NH2 and R1 is hydrogen or alkoxy then R3 is not hydrogen or alkoxy;
- when R2 is CH2CH2NH2 and R3 is hydrogen or alkoxy then R1 is not hydrogen or alkoxy;
- and R1, R2, and R3 are not all hydrogen.
9 more elements
30-31. (canceled)
33-34. (canceled)
37-38. (canceled)
A compound having the formula:
- wherein:
- R1 is hydrogen, alkyl, alkenyl, alkoxy, or alkenoxy;
- R2 is hydrogen, C1-C6 alkyl (CH2NO2)n, C2-C6 alkenyl (CH2NO2)n, C1-C6 alkyl-NHCOCH3, C2-C6 alkenyl-NHCOCH3, cycloalkyl, cycloalkenyl, aryl, heteroaryl, C1-C6 alkyl-NH2, or C2-C6 alkenyl-NH2;
- R3 is hydrogen, CO(C1-C6 alkyl), CO(C2-C6 alkenyl), C1-C6 alkyl-NHCOCH3, C2-C6 alkenyl-NHCOCH3, alkoxy, alkenoxy, C1-C6 alkyl (CH2NO2)n, C2-C6 alkenyl (CH2NO2)n, cycloalkyl, cycloalkenyl, aryl, or heteroaryl;
- R4 is hydrogen, alkoxy or alkenoxy;
- and
- N represents 1, 2, or 3;
- and
- wherein the compound is effective as an antioxidant.
6 more elements
43-47. (canceled)
Dependencies are inferred from the claim text.