Gyrase inhibitors and uses thereof

A compound of formula VII:

• or a pharmaceutically acceptable salt thereof, wherein:
• V is selected from nitrogen, CH, or CF;
• R3 is hydrogen or C1-4 aliphatic, wherein:
• when R3 is Cl1-4 aliphatic, R3 is substituted with 0-3 groups independently selected from OH, R5, or OR5;
• wherein:
• R5 is C1-3 aliphatic, wherein:
• two R5 aliphatic groups may be optionally taken together with the carbon to which they are bound to form a C3-4 cycloalkyl ring;
• provided that if R3 is hydrogen, then V is not nitrogen or CH;
• R4 is a C1-3 aliphatic group;
• and
• Ring C is a 6-membered heteroaryl ring having 1-2 nitrogens, wherein:
• Ring C is substituted with 1-3 groups selected from R6;
• wherein:
• each R6 is independently selected from OR7 or halogen;
• and
• R7 is C1-4 aliphatic;
• or
• Ring C is an unsubstituted 2-pyrimidine ring.