Inactivated and dried biological preparations
OwnerPatrick A. Mach, Tera M. Nordby +1inventors
InventorsPatrick A. Mach, Tera M. Nordby, Mara S. Reif-Wenner
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Abstract
In one aspect, the present invention provides biological sample that includes a dry preparation comprising a stabilizer and stabilized, inactivated biological material. In certain embodiments, the biological material may be heat inactivated and/or heat dried. In another aspect, the present invention provides a method of making a dried biological preparation. Generally, the method includes collecting a sample of biological material, inactivating the biological material, suspending the sample in a volume of a stabilizer and allowing the stabilizer to dry. In certain embodiments, the biological material may be heat inactivated and/or heat dried.
Claims56
A biological sample comprising:
- a dry preparation comprising a stabilizer and stabilized, inactivated biological material.
A method of making a dried biological preparation, the method comprising:
- collecting a sample of biological material;
- inactivating the biological material;
- suspending the sample in a volume of a stabilizer;
- and
- allowing the stabilizer to dry.
A method of performing a positive control in an assay for detecting target biological material, the method comprising:
- providing a dry preparation that comprises a stabilizer and stabilized, inactivated target biological material;
- contacting the inactivated target biological material with an aqueous solution, thereby generating a reconstituted sample;
- and
- performing the assay for detecting the target biological material on the reconstituted sample.
Dependencies are inferred from the claim text.