Pyrrolo[1,2-a]imidazoledione effective in the treatment of peripheral neurotoxicity induced by chemotherapeutic agents
AssigneeNeurotune AG
InventorsCarlo Farina, Carla Ghelardini, Paola Petrillo
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Abstract
The use of a compound of formula (I), is disclosed in treating and/or preventing 5 chemotherapy-induced peripheral neurotoxicity (CIPN). The invention includes pharmaceutical compositions wherein the compound of formula (I) is present in a mixture with anticancer agents. An improved anticancer treatment with reduced CIPN-related side effects is also provided.
Claims24
-10. (canceled)
A pharmaceutical composition comprising a compound of formula (I)
- or a solvate thereof, in combination with one or more anticancer chemotherapeutic agents and optional pharmaceutical excipients, for use in the treatment and/or prevention of peripheral neurotoxicity induced by said chemotherapeutic agents.
-16. (canceled)
A method for the treatment and/or prevention of chemotherapy-induced peripheral neurotoxicity, which comprises:
- administering to a patient in need thereof a medicament containing an effective amount of a compound of Formula (I)
- or a solvate thereof.
A method for the treatment and/or prevention of chemotherapy-induced peripheral neurotoxicity, which comprises:
- administering to a patient in need thereof a medicament containing a compound of formula (I)
- or a solvate thereof, with one or more anticancer chemotherapeutic agents.
Dependencies are inferred from the claim text.