Process for preparing particles containing an antiviral
AssigneeJanssen R&D Ireland
InventorsGaël LAMOUREUX, Gérard Cousin, Daniel Joseph Christiaan Thoné
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Abstract
A process for preparing a particle comprising a co-precipitate surrounding a neutral hydrophilic carrier, said process comprising spraying an organic solution on a neutral hydrophilic carrier, said solution comprising at least one triazine or pyrimidine active ingredient having HIV inhibiting properties, one surface active agent, and one hydrophilic polymer, wherein the spraying of whole of the solution occurs in at least two separate steps, each of these steps followed by a grinding step of the product obtained at the end of the preceding step.
Claims17
A process for preparing a particle according to claim 10, said process comprising spraying an organic solution on a neutral hydrophilic carrier, said solution comprising at least one triazine or pyrimidine active ingredient having HIV inhibiting properties, one surface active agent, and one hydrophilic polymer, wherein the spraying of whole of the solution occurs in at least two separate steps, each of these steps followed by a grinding step of the product obtained at the end of the preceding step.
A particle comprising a co-precipitate applied in a layer surrounding a neutral hydrophilic carrier, and comprising at least one antiviral selected from the group consisting of pyrimidine and triazine, at least one surface-active agent, and at least one hydrophilic polymer, said particle prepared by a process comprising spraying an organic solution on a neutral hydrophilic carrier, said solution comprising at least one triazine or pyrimidine active ingredient having HIV inhibiting properties, one surface active agent, and one hydrophilic polymer, wherein the spraying of whole of the solution occurs in at least two separate steps, each of these steps followed by a grinding step of the product obtained at the end of the preceding step.
(canceled)
Dependencies are inferred from the claim text.