Method For Making Cetirizine Tablets
AssigneeMcNeil-PPC, Inc.
InventorsKenneth Day, Kangping Xiao, Satish Kamath, Indu Shah
Life of this patent
Estimating the term…
Abstract
In one aspect, the present invention features a method of producing a tablet including cetirizine including the steps of: (i) mixing cetirizine, a polyol, and a solvent for the cetirizine to form a cetirizine:polyol complex, wherein the solvent comprises water and an alkalizing agent and has a pH from about 2 to about 7; (ii) isolating particles of the cetirizine:polyol complex from the mixture; and (iii) forming the particles into a tablet.
Claims20
A method of producing a tablet comprising cetirizine, said method comprising the steps of:
- (i) mixing cetirizine, a polyol, and a solvent for said cetirizine to form a cetirizine:polyol complex, wherein said solvent comprises water and an alkalizing agent and has a pH from about 2.5 to about 4;
- (ii) isolating particles of said cetirizine:polyol complex from said mixture;
- and
- (iii) forming said particles into a tablet.
A method of claim 15, wherein said tablet is formed by compressing said particles.
Dependencies are inferred from the claim text.