S-Nitrosothiols Containing Composition for the Treatment of Fatty Liver Diseases, Obesity and Other Diseases Associated with the Metabolic Syndrome and the Use of Such Compositions
AssigneeProtagen AG
InventorMarcelo Ganzarolli De Oliveira
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Abstract
The present invention refers to pharmaceutical compositions containing S-nitrosothiols as active principle. The referred compositions are intended for the treatment of the fatty liver disease and other diseases associated with the metabolic syndrome. The composition is administered either orally or rectally.
Claims32
-31. (canceled)
Pharmaceutical composition with nitrosating action capable of modifying the action of enzymes involved in the synthesis and transport of lipids in the liver characterized by comprising in their active principle a pharmaceutically effective amount of the equimolar mixture of a nitrosable thiol and sodium nitrite, conjunctly dissolved in water, thus generating the S-nitrosothiols, which are effective in the treatment and/or prevention of the Fatty Liver Diseases and other diseases associated with the metabolic syndrome.
Dependencies are inferred from the claim text.