Cholestanol derivative for combined use
AssigneesOtsuka Pharmaceutical Co., Ltd., National University Corporation Gunma University
InventorsShin YAZAWA, Toyo Nishimura, Takayuki Asao
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Abstract
The invention provides a cancer chemotherapeutic agent which has fewer side effects and excellent efficacy. The cancer chemotherapeutic agent of the invention includes a cholestanol derivative represented by formula (1): (wherein G represents GlcNAc-Gal-, GlcNAc-Gal-Glc-, Fuc-Gal-, Gal-Glc-, Gal-, or GlcNAc-) or a cyclodextrin inclusion compound thereof, and an anti-cancer agent.
Claims10
A cancer chemotherapeutic agent comprising, in combination, a cholestanol derivative represented by formula (1):
- (wherein G represents GlcNAc-Gal-, GlcNAc-Gal-Glc-, Fuc-Gal-, Gal-Glc-, Gal-, or GlcNAc-) or a cyclodextrin inclusion compound thereof, and an anti-cancer agent.
The method of producing a chemotherapeutic agent for the treatment of cancer, by combining a cholestanol derivative represented by formula (1):
- (wherein G represents GlcNAc-Gal-, GlcNAc-Gal-Glc-, Fuc-Gal-, Gal-Glc-, Gal-, or GlcNAc-) or a cyclodextrin inclusion compound thereof and an anti-cancer agent.
The cancer chemotherapy, comprising administering, in combination, a cholestanol derivative represented by formula (1):
- (wherein G represents GlcNAc-Gal-, GlcNAc-Gal-Glc-, Fuc-Gal-, Gal-Glc-, Gal-, or GlcNAc-) or a cyclodextrin inclusion compound thereof and an anti-cancer agent, to a patient in need thereof.
Dependencies are inferred from the claim text.