Biologically Active Hemagglutinin From Type A Clostridium Botulinum and Methods of Use
AssigneeUniversity of Massachusetts, a Massachusetts corporation
InventorsBal Ram Singh, Shashi Kant Sharma
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Abstract
An isolated, biologically active 33 kDa hemagglutinin purified from the type A Clostridium botulinum neurotoxin complex and its uses are described.
Claims23
A composition comprising an isolated, biologically active Hn-33 from type A Clostridium botulinum and a neurotoxin.
An isolated, biologically active Hn-33 of type A Clostridium botulinum.
A method of eliciting an immune response against a neurotoxin in an animal, the method comprising administering to the animal an amount of a composition effective to elicit an immune response against the neurotoxin, the composition comprising an isolated, biologically active Hn-33 of type A Clostridium botulinum and a neurotoxin.
A method of treating or preventing a neuromuscular condition in an animal, the method comprising administering to the animal an amount of a composition effective to treat or prevent the neuromuscular condition, the composition comprising an isolated, biologically active Hn-33 of type A Clostridium botulinum and a neurotoxin.
Dependencies are inferred from the claim text.