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US 2010/0061931 A1Published application
Method for the use of [11c] carbon monoxide in labeling synthesis of 11c-labelled esters by photo-induced free radical carbonylation
OwnerBengt Langstrom, Oleksiy Itsenko +1inventors
InventorsBengt Langstrom, Oleksiy Itsenko, Tor Kihlberg
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Abstract
Methods and reagents for photo-initiated carbonylation with carbon-isotope labeled carbon monoxide using alkyl/aryl iodides with alcohols pretreated by a base are provided. The resultant carbon-isotope labeled esters are useful as radiopharmaceuticals, especially for use in Positron Emission Tomography (PET). Associated kits for PET studies are also provided.
Claims9
-12. (canceled)
A carbon-isotope labeled compound of formula (III),
- wherein R is linear or cyclic alkyl or substituted alkyl, aryl or substituted aryl
A kit for PET study comprising a carbon-isotope labeled compound of formula (III),
- wherein R is linear or cyclic alkyl or substituted alkyl, aryl or substituted aryl
Dependencies are inferred from the claim text.