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US 2010/0010200 A1Published application
Interleukin-18 binding proteins, their preparation and use
AssigneeYeda Research and Development Co. Ltd.
InventorsDaniela Novick, Charles Dinarello, Menachem Rubinstein, Soo Hyun Kim
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Abstract
Interleukin-18 binding proteins which are capable of binding IL-18 and/or modulating and/or blocking IL-18 activity are provided. Methods for their isolation and recombinant production, DNAs encoding them, DNA vectors expressing them, vectors useful for their expression in humans and other mammals, antibodies against them are also provided.
Claims7
An antibody to IL-18BP, wherein the IL-18BP is capable of at least one of the following:
- (i) binding to IL-18,
- (ii) modulating the activity of IL-18,
- (iii) blocking the activity of IL-18.
Dependencies are inferred from the claim text.