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AssigneeKorea Advanced Institute of Science and Technology
InventorsSang Yup Lee, Hee Tae Jung, Dae Hwan Jung, Young Koan Ko, Do Hyun Kim, Seok Jae Lee, Byung Hun Kim, Jae Shin Lee
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Conductive carbon nanotubes (CNTs) obtained by dotting carboxylated CNTs with metal nanocrystals by chemical functional groups, are described, as well as a method for fabricating a pattern or film of the conductive CNTs which involves repeatedly depositing conductive CNTs on a substrate to achieve high surface density. A biosensor is described, in which bioreceptors that bind to target biomolecules are selectively attached to conductive CNTs or a conductive CNT pattern or film. By use of the conductive biosensor, various target biomaterials that bind or react with the bioreceptors can be precisely measured directly or by electrochemical signals at large amounts in one step. Additionally, the biosensor can be used for an electrical detection method capable of providing precise measurement results even with a small amount of source material.
A method for producing CNTs dotted with a metal, which includes the steps of:
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A conductive carbon nanotube (CNT)-biosensor in which bioreceptor that bind or react with target biomaterials are attached to (i) a conductive CNT pattern, having a structure of substrate-[CONH—R2—S-M-CNT-M-(S—R3—S-M-CNT-M)p]q or (ii) a conductive carbon nanotube (CNT) film, having a structure of substrate-[CONH—R2—S-M-CNT-M-(S—R3—S-M-CNT-M)p]q;
A method for fabricating a conductive CNT-biosensor, which comprises attaching a bioreceptor that bind to or react with target biomaterials to any one selected from the group consisting of the following:
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A method for fabricating a nucleic acid chip, which comprises attaching a conductive CNT-M-nucleic acid complex wherein a nucleic acid is attached to the metal (M) of conductive CNTs having a form CNT-(CONH—R1—S-M)r, wherein M represents a metal, r is a natural number greater than 1, and R1 represents a divalent moiety selected from among C1-20 saturated hydrocarbons, unsaturated hydrocarbons and aromatic organic groups, to a substrate having amine/lysine groups attached to its surface.
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A CNT-M-enzymatic substrate complex, wherein an enzymatic substrate is attached to the metal (M) of conductive CNTs having a form of CNT-(CONH—R1—S-M)r.
The CNT-M-enzymatic substrate complex, wherein the enzymatic substrate is kinase substrate peptide (SP).
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Dependencies are inferred from the claim text.