US 2009/0312276 A1Published application

Compositions and Methods for Treating Cancer

AssigneeThreshold Pharmaceuticals, Inc.

InventorsMark Matteucci, Photon Rao, Jian-Xin Duan

Life of this patent

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Hypoxia-activated prodrugs can be used to treat cancer when administered alone or in combination with one or more anti-neoplastic agents.

Dependent claims

A protected anti-neoplastic agent of the formula Hyp-N, wherein

Dependencies are inferred from the claim text.

A61K 31/415
Having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole: 1,2-Diazoles
A61K 31/4166
1,3-Diazoles: having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
A61K 31/44
Having six-membered rings with one nitrogen as the only ring hetero atom: non condensed pyridines; Hydrogenated derivatives thereof
A61K 31/5377
1,4-Oxazines, e.g. morpholine: not condensed and containing further heterocyclic rings, e.g. timolol

From the US filing history. Foreign family members aren’t listed.

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