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US 2009/0311284 A1Published application
Recombinant Viral Proteins And Particles
AssigneeAcademia Sinica
InventorsShu-Mei Liang, Na-sheng Lin, Yau-heiu Hsu, Jia-Teh Liao
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Abstract
Disclosed are nucleic acids encoding fusion polypeptides containing the sequence of a Bamboo mosaic virus coat protein or a segment thereof; and an immunogenic heterologous fragment that is fused to the carrier fragment. Also disclosed are related chimeric bamboo mosaic virus particle, related expression vectors, related host cells, and related compositions. Methods of producing and using the fusion polypeptide or chimeric Bamboo mosaic virus particle are also disclosed.
Claims26
An isolated nucleic acid encoding a fusion polypeptide, wherein the fusion polypeptide includes
- a carrier fragment that contains the sequence of a Bamboo mosaic virus coat protein or contains a segment thereof;
- and
- an immunogenic heterologous fragment that is fused to the carrier fragment and at least 3 amino acids in length.
Dependencies are inferred from the claim text.