Galactose derivative, drug carrier and medicinal composition
AssigneeNippon Shinyaku Co., Ltd.
InventorsTadaaki Ohgi, Toshihiro Ueda, Satoru Sonoke
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AssigneeNippon Shinyaku Co., Ltd.
InventorsTadaaki Ohgi, Toshihiro Ueda, Satoru Sonoke
Estimating the term…
The object of the present invention is to provide a novel and useful galactose derivative, which is a component of a drug carrier by which a medicine can be efficiently transferred into the liver, a drug carrier comprising the derivative, and a pharmaceutical composition comprising the drug carrier and a medicine. The present invention relates to a galactose derivative represented by the following general formula (I) a drug carrier comprising the derivative and a cationic lipid, and a pharmaceutical composition comprising the carrier and a medicine (preferably a double-stranded RNA, a double-stranded DNA, an oligo nucleic acid). wherein, R1 represents hydrogen, an alkyl having 1 to 10 carbons which may be substituted or 1-(D)-deoxylactito-1-yl; R2 represents a saturated or unsaturated fatty acid residue having 10 to 30 carbon atoms.
A galactose derivative represented by general formula (I)
Dependencies are inferred from the claim text.