Oxadiazolyl-phenoxyalkylisoxazoles, compositions thereof and methods for their use as anti-picornaviral agents
OwnerGerald Rhodes, Theodore J. Nitzinventors
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Abstract
Oxadiazolyl-phenoxyalkylisoxazoles and pharmaceutically acceptable salts thereof, compositions comprising oxadiazolyl-phenoxyalkylisoxazole compounds or pharmaceutically acceptable salts thereof and methods for using oxadiazolyl-phenoxyalkylisoxzazole compounds or pharmaceutically acceptable salts thereof as anti-picornaviral agents are described herein. The methods include using pleconaril as a prodrug for conversion to anti-picornaviral compounds in vivo.
Claims8
-19. (canceled)
A method for preventing a picornaviral infection in a patient, said method comprising administering to a patient in need of such prevention an effective amount of the compound of Formula I:
- or a pharmaceutically acceptable salt thereof.
A method for preventing a picornaviral infection in a patient, said method comprising administering to a patient in need of such prevention an effective amount of the compound of Formula II:
- or a pharmaceutically acceptable salt thereof.
A method of using pleconaril as a prodrug for preventing picornaviral infections in a patient, said method comprising administering to said patient an effective amount of pleconaril or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.