Composition and method of treating facial skin defect
OwnerApostolos Pappas, Druie E. Cavender +1inventors
InventorsApostolos Pappas, Druie E. Cavender, Miri Seiberg
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Abstract
This invention relates to a subcutaneous deliverable composition containing an agonist of the peroxisome proliferator-activated receptor-gamma, and a method for treating facial skin defects in a mammalian subject using the subcutaneous deliverable composition.
Claims14
A method for treating the appearance of a facial skin defect in a mammalian subject, wherein said method comprises:
- a) providing a subcutaneous deliverable composition comprising from about 0.00001% to about 5% by weight of an agonist of the peroxisome proliferator-activated receptor-gamma selected from the group consisting of rosiglitazone, ciglitazone troglitazone, englitazone, pioglitazone, linoleic acid, oxidized metabolites of linoleic and arachidonic acid, and mixtures thereof, from about 1% to about 10% by weight of a dermal filling material and a pharmaceutically acceptable carrier;
- b) identifying an area of facial skin in need of the treatment in said subject;
- c) delivering a safe and cosmetically effective amount of said composition subcutaneously to said area of skin, wherein said delivery results in a reduction of said appearance of facial skin defect.
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A method of facial contouring in a mammalian subject, wherein said method comprises:
- a) providing a subcutaneous deliverable composition comprising an agonist of the peroxisome proliferator-activated receptor-gamma, and a pharmaceutically acceptable carrier;
- b) identifying an area of facial skin in need of the treatment in said subject;
- c) delivering a safe and cosmetically effective amount of said composition subcutaneously to said area of skin, wherein said delivery results in an improvement of facial contour around said area of facial skin.
A subcutaneous deliverable composition for treating an appearance of skin defect in a mammalian subject, said deliverable composition comprising:
- a) an agonist of the peroxisome proliferators-activated receptor-gamma, b) a dermal filling material;
- and c) a pharmaceutically acceptable carrier, wherein the delivery of said composition results in a reduction of the appearance of skin defect around said area of facial skin
Dependencies are inferred from the claim text.