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US 2009/0286313 A1Published application
Non-steroidal anti-inflammatory drug activated gene with anti-tumorigenic properties
AssigneesThe United States of America, as represented by the Secretary, Department of Health and Human, Service
InventorsThomas E. Eling, Seung Joon Baek
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Abstract
The present invention provides methods and compositions for drug screens to identify and characterize agents that are agonistic or antagonistic to activation of the promoter region of the NAG-1 gene. Activation of the NAG-1 gene is associated with the apoptotic elimination of cancer cells both in vitro and in vivo. The invention also provides novel promoter region sequences of the NAG-1 gene.
Claims4
1-14. (canceled)
An isolated or purified antibody reactive with a polypeptide encoded by a nucleic acid sequence comprising SEQ ID NO:
- 2.
Dependencies are inferred from the claim text.