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OwnerHiroyuki YOKOI, Masanori MIZUNO +1inventors
InventorsHiroyuki YOKOI, Masanori MIZUNO, Toyokazu HAGA
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It is an object of the present invention to provide (1) a process for manufacturing alkali metal salts of 2-[{4-(3-methoxypropoxy)-3-methylpyridin-2-yl}methylsulfinyl]-1H-benzimidazole which are useful as gastric acid secretion inhibitors, anti-ulcer agents and other drugs and (2) salts of 2-[{4-(3-methoxypropoxy)-3-methylpyridin-2-yl}methylsulfinyl]-1H-benzimidazole with amines which are intermediates for the production of the alkali metal salts, and a process for manufacturing the same. According to the present invention, disclosed are salts represented by the following formula (I): (wherein A+ represents an isopropylammonium ion, sec-butylammonium ion or cyclopentylammonium ion).
A process for manufacturing salt comprising a salt-producing step, wherein the salt-producing step is accomplished in an ester solvent, a nitrile solvent, an ether solvent, an alcohol solvent, a ketone solvent, an aliphatic hydrocarbon solvent, an aromatic hydrocarbon solvent, water or a mixed solvent of the foregoing to produce the salt represented by the following formula (I):
A process for manufacturing a salt comprising a salt-producing step, wherein the salt-producing step is accomplished in ethyl acetate, n-butyl acetate, diethyl carbonate, acetonitrile, t-butylmethyl ether, isopropanol, hexane, tetrahydrofuran, toluene or a mixed solvent of the foregoing to produce the salt represented by the following formula (I):
Dependencies are inferred from the claim text.