Back to results
US 2009/0264485 A1Published application
Pyrazole Derivatives, Their Manufacture and Their Use as Pharmaceutical Agents
OwnerHans-Willi Krell, Joerg Middeldorff +3inventors
InventorsHans-Willi Krell, Joerg Middeldorff, Ulrike Reiff, Thomas von Hirschheydt, Edgar Voss
Life of this patent
Estimating the term…
Abstract
Objects of the present invention are the compounds of formula I their pharmaceutically acceptable salts, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, pharmaceutical compositions containing them and their manufacture, as well as the use of the above-mentioned compounds in the control or prevention of illnesses such as cancer.
Claims8
A compound according to formula I,
- wherein
- R1 is selected from the group consisting of halogenated alkyl, halogenated alkoxy, and halogen;
- R2 is selected from the group consisting of hydrogen and halogen;
- R3 is selected from the group consisting of hydrogen and alkyl;
- R4 is alkyl;
- and
- W is selected from the group consisting of —O—, —S—, —S(O)—, and —S(O)2—;
- or a pharmaceutically acceptable salt thereof.
5 more elements
A process for the manufacture of a compound of formula I,
- wherein
- the compound of formula V,
- is reacted with a compound of formula IV,
- and wherein
- R1 is selected from the group consisting of halogenated alkyl halogenated alkoxy, and halogen;
- R2 is selected from the group consisting of hydrogen and halogen;
- R3 is selected from the group consisting of hydrogen and alkyl;
- R4 is alkyl;
- and
- W is selected from the group consisting of —O—, —S—, and —S(O)—.
7 more elements
8-9. (canceled)
Dependencies are inferred from the claim text.