US 2009/0264394 A1Published application

Nitrooxy derivatives of glucocorticoids

AssigneesNicox S.A., Ferrer Internacional, S.A.

InventorsFrancesca Benedini, Ennio Ongini, Antonio Guglietta, Daniel Palop, Marta Princep

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Abstract

The invention relates to new steroids nitrooxyderivatives, to topical pharmaceutical formulations thereof, and their use for treating skin or mucosal membrane diseases or disorders. These new steroids nitrooxyderivatives have an improved pharmacological activity and enhanced local tolerability.

Claims7

Dependent claims

((11β, 16β)-9-fluoro-11-hydroxy-16-methyl-21-[1-oxo-[4(nitrooxymethyl)benzoxyJ-17-(valeryloxy)pregna-1,4-diene-3,20-dione.

Dependencies are inferred from the claim text.

Facts

Application: 12/492,404Filed 26 Jun 2009
Priority: EP 05019155.02 Sep 2005
Published: 22 Oct 2009
Term ends: Not estimatedThe source records don’t support an estimate.

Classification12 codes

C07J 43/003
Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopentahydrophenanthrene skeleton: not condensed
A61P 5/44
Of the suprarenal hormones: glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids
A61P 17/00
Drugs for dermatological disorders
A61P 17/04
Drugs for dermatological disorders: antipruritics

Family

Application12/065,561Continuation · filed 3 Mar 2008
Application12/492,404Continuation
US 2008/0221073 A1Published application
US 2009/0264394 A1This patent

From the US filing history. Foreign family members aren’t listed.

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