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US 2009/0264387 A1Published application
Estra-1,3,5(10)-triene derivatives for contraception
AssigneeGrüNenthal GmbH
InventorsTamara Pfaff, Thomas Otten
Life of this patent
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Abstract
The invention relates to pharmaceutical compositions and administration forms, which contain compounds of the general formula (I) and methods for contraception by administering these administration forms. The invention additionally relates to compounds of the general formula (I) as medication and the use of these compounds for the production of drugs for hormone replacement therapy.
Claims15
A pharmaceutical composition comprising at least one physiologically compatible adjuvant and at least one compound of the formula (I)
- wherein
- R1 and R6, respectively independently of one another, are selected from —H, a —C1-C12 hydrocarbon or a —CO—C1-C12 hydrocarbon;
- R2, R3, R4 and R5, respectively independently of one another, are selected from —H, —OH, a —O—C1-C12 hydrocarbon or a —O—CO—C1-C12 hydrocarbon;
- wherein the —C1-C12 hydrocarbon, respectively independently of one another, are aliphatic or aromatic;
- and is unsubstituted or substituted with one or more substituents, which are selected independently of one another from the group consisting of halogen and —OH;
- wherein said compound is optionally in the form of a stereoisomer or mixture thereof, respectively in the form of a free compound or a physiologically compatible salt or solvate thereof.
3 more elements
The pharmaceutical composition according to, additionally comprising oestrogen.
(canceled)
Dependencies are inferred from the claim text.